The genetics of caloric restriction in Caenorhabditis elegans.

doi:10.1073/pnas.95.22.13091

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Article

The genetics of caloric restriction in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 27 Oct 1998

Lakowski B, Hekimi S

Abstract excerpt

Low caloric intake (caloric restriction) can lengthen the life span of a wide range of animals and possibly even of humans. To understand better how caloric restriction lengthens life span, we used genetic methods and criteria to investigate its mechanism of action in the nematode Caenorhabditis...

Topics

Aging
Alleles
Animals
Caenorhabditis elegans
Disorders of Sex Development
Energy Intake
Feeding Behavior
Female
Genes, Helminth
Longevity
Mutation
Oviposition

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