Article

WDFY3 cell autonomously controls neuronal migration

2022-02-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Proper cerebral cortical development depends on the tightly orchestrated migration of newly born neurons from the inner ventricular and subventricular zones to the outer cortical plate. Any disturbance in this process during prenatal stages may lead to neuronal migration disorders (NMDs), which can vary in extent from focal to global. Furthermore, NMDs show a sub...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4c48ac29-88b2-5f38-b35e-c0c91e8bbe68
DOI: 10.21203/rs.3.rs-1316167/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

WDFY3 cell autonomously controls neuronal migrationDOI 10.21203/rs.3.rs-1316167/v1Read

WDFY3 mutation alters laminar position and morphology of cortical neurons.Semantic proximity Read

Tissue-wide Effects Overrule Cell-intrinsic Gene Function in Cortical Projection Neuron MigrationSemantic proximity Read

Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size.Semantic proximity Read

Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.Semantic proximity Read

Cortical neuronal migration mutants suggest separate but intersecting pathways.Semantic proximity Read

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development.Semantic proximity Read

disabled-1 functions cell autonomously during radial migration and cortical layering of pyramidal neurons.Semantic proximity Read

Disruption of the transcription factor <i>NEUROD2</i> causes an autism syndrome via cell-autonomous defects in cortical projection neuronsSemantic proximity Read

X-linked neuronal migration disorders: Gender differences and insights for genetic screening.Semantic proximity Read

Nanoscopic Clustering of Neuroligin-3 and Neuroligin-4X Regulates Growth Cone Organization and SizeSemantic proximity Read

Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling.Semantic proximity Read

Automated deep-phenotyping of the vertebrate brain.Semantic proximity Read