Article

Predicting mechanisms of action at genetic loci associated with discordant effects on type 2 diabetes and abdominal fat accumulation

2022-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Metabolic syndrome (MetSyn) is a cluster of dysregulated metabolic conditions that occur together to increase the risk for cardiometabolic disorders such as type 2 diabetes (T2D). One key condition associated with MetSyn, abdominal obesity, is measured by computing the ratio of waist-to-hip circumference adjusted for the body-mass index (WHRadjBMI). WHRadjBMI and T2D are complex traits with gene...

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Literature Corpus work: 4c1e08ca-f828-5a93-aafb-463888f819f8
DOI: 10.1101/2022.04.27.489778

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