Finishing a complete giraffe genome from telomere to telomere with Verkko-Fillet

Abstract excerpt

High-quality reference genomes are critical for studying the biology of the genome, but current methods often leave gaps and errors, especially in repetitive regions. These issues arise from challenges in genome graph curation and are not fully resolvable by standard polishing approaches. To address this, we developed Verkko-Fillet, a Python-based interactive framework for inspecting, editing, and refining genome...

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• Share to Chromosomal and Genetic Variations
• Share to Mitochondrial Function and Pathology
• Share to Telomeres, Telomerase, and Senescence