Article

Spatial transcriptomic profiling of vascular compartments of chronic antibody-mediated rejection in kidney allografts identified compartment-specific signatures: a pilot study

2026-08-18

Abstract excerpt

<title>Abstract</title> <p> Despite being a major cause of kidney allograft failure, compartment-specific molecular signatures underlying chronic active antibody-mediated rejection (CAMR) remain incompletely characterized. We used GeoMx digital spatial profiling (18,677 genes) to analyze transcriptomic differences in glomeruli, peritubular capillaries, and vessels from four renal allografts with varying donor-sp...

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Literature Corpus work: 4bed7bd4-9ff9-59d3-a438-fb84aeaccd08
DOI: 10.21203/rs.3.rs-10222591/v1

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