Article

Three-dimensional imaging and single-cell transcriptomics of the human kidney implicate perturbation of lymphatics in alloimmunity

2022-10-28

Abstract excerpt

<h4>ABSTRACT</h4> Studies of the structural and molecular features of the lymphatic vasculature, which clears fluid, macromolecules and leukocytes from the tissue microenvironment, have largely relied on animal models, with limited information in human organs beyond traditional immunohistochemical assessment. Here, we use three-dimensional imaging and single-cell RNA-sequencing to study lymphatics in the human ki...

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Literature Corpus work: 615e3d34-7fed-5542-85d7-8b89eaf235a4
DOI: 10.1101/2022.10.28.514222

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