Article

Peripheral transcriptomic signature of chronic antibody-mediated rejection in kidney transplantation: a dual effect for <i>MMP9</i> over time

2025-11-07

Abstract excerpt

<h4>BACKGROUND</h4> Chronic antibody-mediated rejection (CAMR) is the main cause of late kidney allograft loss, and no specific effective treatment has been identified so far. Here, we proposed to explore the non-invasive peripheral blood transcriptome signature of CAMR. <h4>METHODS</h4> First, we compared PBMC gene expression from bulk RNA-seq between 35 patients experiencing late CAMR (mean=7.1 years) vs. 43 p...

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Literature Corpus work: e4e516d5-2aaf-5514-9d26-c1fe9881a7d2
DOI: 10.1101/2025.11.06.25339648

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