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Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting

28 Mar 2022

Abstract excerpt

Cutibacterium acnes (C. acnes) is a gram-positive bacterium and a member of the human skin microbiome. Despite being the most abundant skin commensal, certain members have been associated with common inflammatory disorders such as acne vulgaris. The availability of the complete genome sequences from various C. acnes clades have enabled the identification of putative methyltransferases, some of them potentially...

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PMID: 35344565
DOI: 10.1371/journal.ppat.1010420

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