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Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation

2023-05-25

Abstract excerpt

Inflammation upon infectious lung injury is a double-edged sword: while tissue-infiltrating immune cells and cytokines are necessary to control infection, these same factors often aggravate injury. Full appreciation of both the sources and targets of inflammatory mediators is required to facilitate strategies to maintain antimicrobial effects while minimizing off-target epithelial and endothelial damage. Recognizi...

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Literature Corpus work
4bac99d2-a2b5-5d30-be9b-a75e00a879f6
DOI
10.1101/2023.05.25.541966
Open publication

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Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage ActivationDOI 10.1101/2023.05.25.541966
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