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Spatiotemporal landscape of SARS-CoV-2 pulmonary infection reveals <i>Slamf9</i> <sup>+</sup> <i>Spp1</i> <sup>+</sup> macrophages promoting viral clearance and inflammation resolution

2022-05-03

Abstract excerpt

While SARS-CoV-2 pathogenesis has been intensively investigated, the host mechanisms of viral clearance and inflammation resolution are still elusive because of the ethical limitation of human studies based on COVID-19 convalescents. Here we infected Syrian hamsters by authentic SARS-CoV-2 and built an ideal model to simulate the natural recovery process of SARS-CoV-2 infection from severe pneumonia 1,2 . We deve...

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Literature Corpus work
f687795f-cccc-5dc8-a9d7-b6fab0902b6e
DOI
10.1101/2022.05.03.490381
Open publication

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Spatiotemporal landscape of SARS-CoV-2 pulmonary infection reveals <i>Slamf9</i> <sup>+</sup> <i>Spp1</i> <sup>+</sup> macrophages promoting viral clearance and inflammation resolutionDOI 10.1101/2022.05.03.490381
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