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Article

Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum.

Microbiology (Reading, England) - 1 Sept 2004

Fajardo Marcela, Schleicher Michael, Noegel Angelika, Bozzaro Salvatore, Killinger Silke, Heuner Klaus, Hacker Jörg, Steinert Michael

Abstract excerpt

The haploid amoeba Dictyostelium discoideum is a versatile host system for studying cellular aspects of Legionella pathogenicity. Previous studies have shown that the internalization of L. pneumophila leads to an endoplasmic reticulum (ER)-derived organelle that supports intracellular replication of the bacteria. In this study a roadmap of host-cell factors involved in this process was developed. Phagocytosis...

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Identifiers

PMID: 15347742
DOI: 10.1099/mic.0.27111-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum.PMID 15347742Read ↗

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