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Article

Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection.

Cellular microbiology - 1 Nov 2007

Hagedorn Monica, Soldati Thierry

Abstract excerpt

Mycobacterium marinum, a close relative of Mycobacterium tuberculosis, provides a useful model to study the pathogenesis of tuberculosis in genetically tractable model organisms. Using the amoeba Dictyostelium discoideum as a host, we show that expression of the M. marinum protein MAG24-1 is crucial to interfere with phagosome maturation. We find that two host proteins - the flotillin homologue vacuolin and p80,...

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Source

Identifiers

PMID: 17587329
DOI: 10.1111/j.1462-5822.2007.00993.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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