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Pseudopaline-mediated zinc uptake by <i>Pseudomonas aeruginosa</i> determines specific clinically relevant phenotypes and infection outcome

2025-01-08

Abstract excerpt

<h4>AUTHOR SUMMARY</h4> The host-pathogen interface is a biological niche in which two entities competes for essential resources. The host’s nutritional immunity restrict access to metals, while a successful pathogen overcomes these restrictions using dedicated uptake pathways. Pseudopaline is a high-affinity metallophore allowing Pseudomonas aeruginosa to acquire zinc in chelated environments. We demonstrate th...

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Literature Corpus work
5e1463d4-7d45-5af7-af3a-a5dd3b857c98
DOI
10.1101/2025.01.08.631948
Open publication

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Pseudopaline-mediated zinc uptake by <i>Pseudomonas aeruginosa</i> determines specific clinically relevant phenotypes and infection outcomeDOI 10.1101/2025.01.08.631948
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