Article

The tuberculosis-associated microenvironment promotes HIV-1 persistence by impairing CD8+ T cell-mediated viral control

2025-10-15

Abstract excerpt

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is the most common coinfection in people living with HIV-1 (PLWH). This coinfection is associated with accelerated HIV-1 disease progression and reduced survival. However, the immunological and virological mechanisms driving this progression are incompletely understood. To address this knowledge gap, using pleural effusion samples from PLW...

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Literature Corpus work: 4b54e2b4-ae38-59ab-bfa1-6aa4dc9505d5
DOI: 10.1101/2025.10.14.682453

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