Article

Proteomic Immune Signatures of Severe HIV-Associated Tuberculosis in Sub-Saharan Africa: A Prospective, Multicenter Analysis from Uganda

2026-01-02

Abstract excerpt

<h4>Objective</h4> Severe tuberculosis (TB) is a major cause of critical illness and death in people living with HIV (PLWH) worldwide. Despite this, the immunopathology of severe HIV-associated TB (HIV/TB) is poorly understood. We aimed to identify an immunopathologic signature of severe HIV/TB in sub-Saharan Africa. <h4>Design and Setting</h4> We analyzed proteomic data from two prospective observational cohort...

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Literature Corpus work: 3f3086f2-9a06-5501-aa0e-d1538f6556b0
DOI: 10.64898/2025.12.31.25343299

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