Article

Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 responses

2021-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Nucleoside modified mRNA combined with Acuitas Therapeutics’ lipid nanoparticles (LNP) have been shown to support robust humoral immune responses in many preclinical animal vaccine studies and later in humans with the SARS-CoV-2 vaccination. We recently showed that this platform is highly inflammatory due to the LNPs’ ionizable lipid component. The inflammatory property is key to support the dev...

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Literature Corpus work: 4b539ebd-703d-566f-b777-186a43ea756b
DOI: 10.1101/2021.08.01.454662

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Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 responsesDOI 10.1101/2021.08.01.454662Read

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