Article

Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans

2024-05-16

Abstract excerpt

<h4>Importance</h4> Recently, the Food and Drug Administration gave pre-marketing approval to algorithm based on its purported ability to identify genetic risk for opioid use disorder. However, the clinical utility of the candidate genes comprising the algorithm has not been independently demonstrated. <h4>Objective</h4> To assess the utility of 15 variants in candidate genes from an algorithm intended to predic...

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Literature Corpus work: 4b2412ec-016f-5cd0-b7f8-86bf1bd97bfc
DOI: 10.1101/2024.05.16.24307486

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