Article

Sevoflurane inhibition of the developmentally expressed neuronal sodium channel Na <sub>v</sub> 1.3

2025-04-15

Abstract excerpt

Neuronal voltage-gated sodium channels (Na v ) are major targets for the neurophysiological actions of general anesthetics. In the adult brain, cell type-specific effects on synaptic transmission are attributed to the differential sensitivity to volatile anesthetics of specific Na v subtypes preferentially expressed in mature neurons (Na v 1.1, Na v 1.2, Na v 1.6). Compared to mature neurons, neurons in the d...

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Literature Corpus work: 06e57f25-e66f-5ce0-97fe-7b6709c584c2
DOI: 10.1101/2025.04.10.648240

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