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Article

Armc5 deletion causes developmental defects and compromises T-cell immune responses.

Nature communications - 7 Feb 2017

Hu Yan, Lao Linjiang, Mao Jianning, Jin Wei, Luo Hongyu, Charpentier Tania, Qi Shijie, Peng Junzheng, Hu Bing, Marcinkiewicz Mieczyslaw Martin, Lamarre Alain, Wu Jiangping

Abstract excerpt

Armadillo repeat containing 5 (ARMC5) is a cytosolic protein with no enzymatic activities. Little is known about its function and mechanisms of action, except that gene mutations are associated with risks of primary macronodular adrenal gland hyperplasia. Here we map Armc5 expression by in situ hybridization, and generate Armc5 knockout mice, which are small in body size. Armc5 knockout mice have compromised...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28169274
DOI: 10.1038/ncomms13834
PMCID: PMC5309699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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