Article

Oncofetal Reprogramming: A New Frontier in Cancer Therapy Resistance

2025-12-11

Abstract excerpt

Oncofetal reprogramming has recently emerged as a critical concept in translational cancer research, particu-larly for its role in driving therapeutic resistance across a variety of malignancies. This biological process refers to the pattern of gene expression that is restricted to embryogenesis, but becomes expressed again in a sub-population of cancer cells. These genes are typically suppressed after embryogenes...

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Literature Corpus work: 4adb6928-48aa-550a-8b8d-e04dddae824c
DOI: 10.20944/preprints202512.0937.v1

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