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Article

Reprogramming to developmental plasticity in cancer stem cells.

Developmental biology - 15 Oct 2017

O'Brien-Ball Caitlin, Biddle Adrian

Abstract excerpt

During development and throughout adult life, sub-populations of cells exist that exhibit phenotypic plasticity - the ability to differentiate into multiple lineages. This behaviour is important in embryogenesis, is exhibited in a more limited context by adult stem cells, and can be re-activated in cancer cells to drive important processes underlying tumour progression. A well-studied mechanism of phenotypic...

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Identifiers

PMID: 28774727
DOI: 10.1016/j.ydbio.2017.07.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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