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Lineage Plasticity in Cancer: The Tale of a Skin-Walker

18 Jul 2021

Abstract excerpt

Lineage plasticity, the switching of cells from one lineage to another, has been recognized as a cardinal property essential for embryonic development, tissue repair and homeostasis. However, such a highly regulated process goes awry when cancer cells exploit this inherent ability to their advantage, resulting in tumorigenesis, relapse, metastasis and therapy resistance. In this review, we summarize our current...

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PMID: 34298815
DOI: 10.3390/cancers13143602

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