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Dynamics of human hematopoietic stem and progenitor cell differentiation to the erythroid lineage

10 May 2023

Abstract excerpt

Erythropoiesis, the development of erythrocytes from hematopoietic stem cells, occurs through four phases: erythroid progenitor (EP) development, early erythropoiesis, terminal erythroid differentiation (TED), and maturation. According to the classical model that is based on immunophenotypic profiles of cell populations, each of these phases comprises multiple differentiation states that arise in a hierarchical...

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PMID: 37172755
DOI: 10.1016/j.exphem.2023.05.001

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