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Article

A resource for the conditional ablation of microRNAs in the mouse.

Cell reports - 19 Apr 2012

Park Chong Yon, Jeker Lukas T, Carver-Moore Karen, Oh Alyssia, Liu Huey Jiin, Cameron Rachel, Richards Hunter, Li Zhongmei, Adler David, Yoshinaga Yuko, Martinez Maria, Nefadov Michael, Abbas Abul K, Weiss Art, Lanier Lewis L, de Jong Pieter J, Bluestone Jeffrey A, Srivastava Deepak, McManus Michael T

Abstract excerpt

The importance of miRNAs during development and disease processes is well established. However, most studies have been done in cells or with patient tissues, and therefore the physiological roles of miRNAs are not well understood. To unravel in vivo functions of miRNAs, we have generated conditional, reporter-tagged knockout-first mice for numerous evolutionarily conserved miRNAs. Here, we report the generation...

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Identifiers

PMID: 22570807
DOI: 10.1016/j.celrep.2012.02.008
PMCID: PMC3345170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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