Article
A genomics-based systems approach towards drug repositioning for rheumatoid arthritis.
BMC genomics - 22 Aug 2016
Xu Rong, Wang QuanQiu
Abstract excerpt
BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and destruction of synovial joints. RA affects up to 1 % of the population worldwide. Currently, there are no drugs that can cure RA or achieve sustained remission. The unknown cause of the disease represents a significant challenge in the drug development. In this study, we address this challenge by proposing an...
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