Article

Mitochondrial One-Carbon Flux has a Growth-Independent Role in Promoting Breast Cancer Metastasis

2021-07-12

Abstract excerpt

<title>Abstract</title> <p>Progression of primary cancer to metastatic disease is the most common cause of death in cancer patients with minimal treatment options available. Canonical drugs mainly target the proliferative capacity of cancer cells, which often leaves slow-proliferating, persistent cancer cells unaffected. Thus, we aimed to identify metabolic determinants that enable cell plasticity and foster trea...

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Literature Corpus work: 4aa0269e-a27a-5ce8-b688-28aeb1d68f1d
DOI: 10.21203/rs.3.rs-639444/v1

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