Article

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis

2021-05-27

Abstract excerpt

Progression of primary cancer to metastatic disease is the most common cause of death in cancer patients with minimal treatment options available. Canonical drugs target mainly the proliferative capacity of cancer cells, which often leaves slow-proliferating, persistent cancer cells unaffected. Metabolic determinants that contribute to growth-independent functions supporting resistance and metastatic dissemination...

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Literature Corpus work: b65d048e-5072-5c80-b0c9-577329fae9ca
DOI: 10.1101/2021.05.27.445928

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