Article

Bridging the gap: Enhancing the generalizability of epigenetic clocks through transfer learning

2025-02-20

Abstract excerpt

Changes in DNA methylation patterns exhibit a high correlation with chronological age. Epigenetic clocks, developed through statistical models that estimate epigenetic age using the methylation levels of cytosine-guanine dinucleotide (CpG) sites, have emerged as powerful tools in understanding aging and age-related diseases. Despite their popularity, the generalizability of these clocks across diverse populations...

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Literature Corpus work: 4a960204-9d8e-5fa3-85ab-0fec00a1b8c3
DOI: 10.1101/2025.02.14.25322080

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