Article

Transfer Elastic Net for Developing Epigenetic Clocks for the Japanese Population

2024-05-21

Abstract excerpt

<h4>Motivation</h4> The epigenetic clock evaluates human biological age based on DNA methylation patterns. It takes the form of a regression model where the methylation ratio at CpG sites serves as the predictor, and chronological or adjusted age as the response variable. Due to the large number of CpG sites considered as candidate explanatory variables and their potential correlation, Elastic Net is commonly use...

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Literature Corpus work: 8078c35c-aa64-5368-8210-c216997868dd
DOI: 10.1101/2024.05.19.594899

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