Article

Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration

2023-03-14

Abstract excerpt

Aging progressively modifies the physiological balance of the organism increasing susceptibility to both genetic and sporadic neurodegenerative diseases. These changes include epigenetic chromatin remodeling events that may modify gene transcription. However, how aging interconnects with disease-causing genes is not well known. Here, we found that Su(var)3-9 causes increased methylation of histone H3K9 in the prom...

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Literature Corpus work: 4a8d44da-4c8c-5929-9337-6de5748344c2
DOI: 10.1101/2023.03.14.532519

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Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegenerationDOI 10.1101/2023.03.14.532519Read

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