Article

A putative human infertility allele of the meiotic recombinase DMC1 does not affect fertility in mice

2018-05-04

Abstract excerpt

<h4>ABSTRACT</h4> Whole exome or genome sequencing is becoming routine in clinical situations for identifying mutations underlying presumed genetic causes of disease, including infertility. While this is a powerful approach for implicating polymorphisms or de novo mutations in genes plausibly related to the phenotype, a greater challenge is to definitively prove causality. This is a crucial requisite for treatmen...

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Literature Corpus work: 4a6e59eb-03e1-5612-81df-cd12803730eb
DOI: 10.1101/313890

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