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Article

A framework for high-resolution phenotyping of candidate male infertility mutants: from human to mouse.

Human genetics - 1 Jan 2021

Houston Brendan J, Conrad Donald F, O'Bryan Moira K

Abstract excerpt

Male infertility is a heterogeneous condition of largely unknown etiology that affects at least 7% of men worldwide. Classical genetic approaches and emerging next-generation sequencing studies support genetic variants as a frequent cause of male infertility. Meanwhile, the barriers to transmission of this disease mean that most individual genetic cases will be rare, but because of the large percentage of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32248361
DOI: 10.1007/s00439-020-02159-x
PMCID: PMC9014372

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