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Pan-tissue and -cancer analysis of ROR1 and ROR2 transcript variants identify novel functional significance for an alternative splice variant of ROR1

2021-11-25

Abstract excerpt

<h4>Background</h4> ROR1/2 are putative druggable targets increasing in significance in translational oncology. Expression of ROR1/2 mRNA and transcript variants has not been systematically examined thus far. <h4>Methods</h4> ROR1/2 transcript variant sequences, signal peptides for cell surface localisation, and mRNA and transcript variant expression were examined in 34 transcriptomic datasets including 33 cance...

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Literature Corpus work
4a39b27d-64ab-5a28-91bf-1ee318a258c0
DOI
10.1101/2021.11.24.469652
Open publication

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Pan-tissue and -cancer analysis of ROR1 and ROR2 transcript variants identify novel functional significance for an alternative splice variant of ROR1DOI 10.1101/2021.11.24.469652
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