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Article

ROR1: an orphan becomes apparent

17 May 2022

Abstract excerpt

Since its initial identification in 1992 as a possible class 1 cell-surface receptor without a known parent ligand, receptor tyrosine kinase-like orphan receptor 1 (ROR1) has stimulated research, which has made apparent its significance in embryonic development and cancer. Chronic lymphocytic leukemia (CLL) was the first malignancy found to have distinctive expression of ROR1, which can help distinguish leukemia...

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PMID: 35580162
DOI: 10.1182/blood.2021014760

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