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Article

Functional and clinical significance of ROR1 in lung adenocarcinoma.

BMC cancer - 10 Nov 2020

Schiavone Giovanna, Epistolio Samantha, Martin Vittoria, Molinari Francesca, Barizzi Jessica, Mazzucchelli Luca, Frattini Milo, Wannesson Luciano

Abstract excerpt

BACKGROUND: Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is normally detectable in embryonic tissues and absent in adult tissues. ROR1 was shown to inhibit apoptosis, potentiate EGFR signaling and reported to be overexpressed and associated with poor prognosis in several tumor models. This study aimed to assess the expression of ROR1 in lung adenocarcinoma (AC) patients. METHODS: We analyzed ROR1...

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Identifiers

PMID: 33172431
DOI: 10.1186/s12885-020-07587-6
PMCID: PMC7653802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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