Article

Characterization of lymphoma models for the surface ROR1 expression

2025-11-19

Abstract excerpt

Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a developmental antigen aberrantly expressed in several B-cell malignancies and represents an attractive therapeutic target. Here, we systematically characterized ROR1 expression in a large panel of B-cell lymphoma cell lines and assessed the activity of a ROR1-targeting antibody-drug conjugate (ADC). ROR1 RNA expression was first evaluated using a previous...

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Literature Corpus work: 615f7c12-0a53-598d-81c6-af9d0ad6cc32
DOI: 10.1101/2025.11.19.684505

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