Article

Genetic variation in Interleukin-17A is associated with increased risk and severity of pneumococcal meningitis in children

2019-10-16

Abstract excerpt

<title>Abstract</title> <p>Background Streptococcus pneumonia is a leading cause of bacterial meningitis in children. Interleukin-17 (IL-17) promotes the host’s defense against pneumococcal infections. We investigated whether single nucleotide polymorphisms (SNPs) of IL -17A were associated with pneumococcal meningitis (PM) in Chinese children.Methods Three SNPs of IL-17A promoter rs4711998 (-877A>G), rs8193036 (...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 49e6fdcd-f983-5ecd-b83d-b32084b7a257
DOI: 10.21203/rs.2.16112/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in Interleukin-17A is associated with increased risk and severity of pneumococcal meningitis in childrenDOI 10.21203/rs.2.16112/v1Read

Gene polymorphisms of IL-17A and bacterial meningitis in Angolan children.Semantic proximity Read

The Gene Polymorphism of IL-17 G-152A is Associated with Increased Colonization of Streptococcus pneumoniae in Young Finnish Children.Semantic proximity Read

Association of Serum IL-17A Levels and IL-17/IL-17R Gene Variants with Community-Acquired Pneumonia in Iranian Children.Semantic proximity Read

How many single-nucleotide polymorphisms (SNPs) must be tested in order to prove susceptibility to bacterial meningitis in children? Analysis of 11 SNPs in seven genes involved in the immune response and their effect on the susceptibility to bacterial meningitis in children.Semantic proximity Read

The association of IL-17A polymorphisms with IL-17A serum levels and risk of ischemic strokeSemantic proximity Read

[Relationship between interleukin-17A gene polymorphisms and the susceptibility to childhood asthma].Semantic proximity Read

IL-17A )rs2275913; G197A) gene polymorphism as predictor for disease severity and its correlation with IL-17 serum levels in COVID-19 patients.Semantic proximity Read

An elevated level of Interleukin-17A in a Senegalese malaria cohort is associated with rs8193038 IL-17A genetic variantSemantic proximity Read

Interleukin-17A and -17F single nucleotide polymorphisms associate with susceptibility of asthma in Chinese Han population.Semantic proximity Read

Association between interleukin 17A polymorphisms and susceptibility to rheumatoid arthritis in a Chinese population.Semantic proximity Read

The polymorphism of IL-17 G-152A was associated with childhood asthma and bacterial colonization of the hypopharynx in bronchiolitis.Semantic proximity Read

Association of IL-17A and IL-10 Polymorphisms with Juvenile Idiopathic Arthritis in Finnish Children.Semantic proximity Read