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Association of Serum IL-17A Levels and IL-17/IL-17R Gene Variants with Community-Acquired Pneumonia in Iranian Children.

Genetic testing and molecular biomarkers - 1 Sept 2026

Sharifie Leila, Jafari Maede, Parvaresh Saeedeh, Eskandari Maryam, Hosseininasab Ali, Choopanizadeh Maral, Kalani Mahtab, Kalani Mehdi

Abstract excerpt

BACKGROUND: Because the IL-17/IL-17 receptor (IL-17R) axis is involved in lung inflammation and genetic variants, such as single nucleotide polymorphisms (SNPs), can affect its function, this study examined the associations between IL-17/IL-17R gene SNPs, serum IL-17A levels, and community-acquired pneumonia (CAP) in Iranian children. METHODS: A total of 266 subjects were enrolled in this study, comprising 126...

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Case-Control Studies
Child, Preschool
Community-Acquired Infections
Gene Frequency
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Interleukin-17

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PMID: 42460899
DOI: 10.1177/19450265261469740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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