Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The polymorphism of IL-17 G-152A was associated with childhood asthma and bacterial colonization of the hypopharynx in bronchiolitis.

Journal of clinical immunology - 1 Jul 2010

Chen Jiehua, Deng Yu, Zhao Jing, Luo Zhengxiu, Peng Wansheng, Yang Juan, Ren Luo, Wang Lijia, Fu Zhou, Yang Xiqiang, Liu Enmei

Abstract excerpt

OBJECTIVE: Interleukin (IL)-17 plays an important role in the pathogenesis of asthma. We investigated the association between single-nucleotide polymorphism (SNP) of IL-17 (rs2275913, IL-17 G-152A) and asthma-related traits. Its effect on IL-17 production was also attractive. METHODS: One hundred and sixty eight childhood asthmatic patients, 144 bronchiolitis patients, and 205 healthy controls were recruited in...

Topics

Asthma
Bacteria
Bronchiolitis
Child
Child, Preschool
Female
Genetic Predisposition to Disease
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hypopharynx

Interleukin-17

Male

Moraxella catarrhalis

Mutation, Missense

Polymorphism, Genetic

Polymorphism, Single Nucleotide

Streptococcus pneumoniae

Source

Identifiers

PMID: 20437253
DOI: 10.1007/s10875-010-9391-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20437253-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The polymorphism of IL-17 G-152A was associated with childhood asthma and bacterial colonization of the hypopharynx in bronchiolitis.PMID 20437253Read ↗

The Gene Polymorphism of IL-17 G-152A is Associated with Increased Colonization of Streptococcus pneumoniae in Young Finnish Children.Semantic proximity Read ↗

Single-Nucleotide Polymorphisms of IL-17 Gene Are Associated with Asthma Susceptibility in an Asian Population.Semantic proximity Read ↗

[Relationship between interleukin-17A gene polymorphisms and the susceptibility to childhood asthma].Semantic proximity Read ↗

Associations of IL-2 and IL-4 Expression and Polymorphisms With the Risks of Mycoplasma pneumoniae Infection and Asthma in Children.Semantic proximity Read ↗

The IL-17 G-152A single nucleotide polymorphism is associated with pulmonary tuberculosis in northern Spain.Semantic proximity Read ↗

The effect of genetic variation and mRNA expression of interleukin-17A gene on susceptibility to asthma.Semantic proximity Read ↗

IL-17 polymorphisms and asthma risk: a meta-analysis of 11 single nucleotide polymorphisms.Semantic proximity Read ↗

Interleukin-13 gene polymorphisms and asthma susceptibility in children: a meta-analysis.Semantic proximity Read ↗

Genetic variation in Interleukin-17A is associated with increased risk and severity of pneumococcal meningitis in childrenSemantic proximity Read ↗

Interleukin-17 Genotypes in Egyptian Asthmatic Children at Zagazig University Hospitals.Semantic proximity Read ↗

Associations between interleukin 17A and 17F polymorphisms and asthma susceptibility: A meta-analysis.Semantic proximity Read ↗

Interleukin-17A and -17F single nucleotide polymorphisms associate with susceptibility of asthma in Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.