Article

Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes

2021-04-13

Abstract excerpt

<h4>ABSTRACT</h4> RNA-binding proteins (RBPs) can regulate more than a single aspect of RNA metabolism. We searched for such previously undiscovered multifunctionality within a set of 143 RBPs, by defining the predictive value of RBP abundance for the transcription and translation levels of known RBP target genes across 80 human hearts. This led us to newly associate 27 RBPs with cardiac translational regulation...

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Literature Corpus work: 49c59054-0480-55e3-88f4-30d8e14da6a9
DOI: 10.1101/2021.04.13.439465

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