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Article

Structural Landscape and Deduced Functions of The Cardiac 14-3-3 Protein Interactome

2022-08-18

Abstract excerpt

Rationale: The 14-3-3 protein family is known to interact with many proteins in non-cardiac cell types to regulate multiple signaling pathways, particularly those relating to energy and protein homeostasis; and the 14-3-3 network is a therapeutic target of critical metabolic and proteostatic signaling in cancer and neurological diseases. Although the heart is critically sensitive to nutrient and energy alterations...

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Literature Corpus work
907e4f8d-78be-5151-a19c-8472e29a6794
DOI
10.20944/preprints202208.0343.v1
Open publication

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