Article

Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukemia patients

2020-08-04

Abstract excerpt

<h4>Background</h4> Vast transcriptomics and epigenomics changes are characteristic of human cancers including leukemia. At remission, we assume that these changes normalise so that omics-profiles resemble those of healthy individuals. However, an in-depth transcriptomic and epigenomic analysis of cancer remission has not been undertaken. A striking exemplar of targeted remission induction occurs in chronic myeloi...

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Literature Corpus work: 49805d56-0261-5469-a2f7-35714c2d929e
DOI: 10.1101/2020.07.31.20165597

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