Article

B cells suppress medullary granulopoiesis by an extracellular glycosylation-dependent mechanism

2019-04-09

Abstract excerpt

The immune response relies on the timely integration of cell-intrinsic processes with cell-extrinsic cues. During infection, B cells vacate the bone marrow for the emergency generation of granulocytes. However, it is unclear if cross-talk between B cells and neutrophils also encourages the return to homeostasis. Here, we report that B cells remodel glycans on hematopoietic progenitors to suppress granulopoiesis. H...

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Literature Corpus work: 496b3d4c-2af1-5568-8e69-2952e1b93ece
DOI: 10.1101/604264

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