Article

Rapid Differentiation From Human Induced Pluripotent Stem Cells Into Functional Oligodendrocytes Using Synthetic Modified Olig2 mRNA

2022-01-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Transcription factors (TFs) have been introduced to drive highly efficient differentiation of human induced pluripotent stem cells (hiPSCs) into lineage-specific oligodendrocytes (OLs). However, effective strategies currently rely mainly on genome-integrating viruses. To facilitate the translation of hiPSC-derived OLs into clinical practice, a synthetic modified...

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Literature Corpus work: 48d3af84-bbf9-5fa1-a9a0-aa680533f536
DOI: 10.21203/rs.3.rs-1192447/v1

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