Article

Reprogramming of mouse embryonic fibroblasts into induced oligodendrocyte progenitor cells via nanovector-mediated indirect lineage conversion

2020-06-17

Abstract excerpt

<title>Abstract</title> <p>Background: Axon-wrapping myelin sheath is vital to nerve conduction, loss or dysfunction of it will result in some neurological diseases. Since mature oligodendrocytes (OLs) lack proliferation ability, and oligodendrocyte progenitor cells (OPCs) maintain slow proliferation or quiescence state, transplantation of exogenous OPCs becomes an alternative strategy for curing these diseases....

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Literature Corpus work: 0ea185da-f82b-582c-9e1e-b61db2897808
DOI: 10.21203/rs.3.rs-35533/v1

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