Article
A Congenic C57BL/6 <i>rd1</i> Mouse Model for Retinal Degeneration Research
2025-07-09
Abstract excerpt
Retinitis pigmentosa is an inherited retinal disease caused by thousands of mutations in approximately 100 different genes. The most widely used mouse model for retinitis pigmentosa has the retinal degeneration 1 ( rd1 ) mutation in the Pde6b gene, which elicits rapid retinal degeneration and vision loss. A major limitation of these models is that these rd1 strains are not congenic, which prevents the use of ap...
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Identifiers and source
- Literature Corpus work
- 48b5a18c-d2d9-5c75-bdcf-ec8975506596
- DOI
- 10.1101/2025.07.09.663548