Article
A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice.
Investigative ophthalmology & visual science - 1 May 2018
Moore Bret A, Roux Michel J, Sebbag Lionel, Cooper Ann, Edwards Sydney G, Leonard Brian C, Imai Denise M, Griffey Stephen, Bower Lynette, Clary Dave, Lloyd K C Kent, Hérault Yann, Thomasy Sara M, Murphy Christopher J, Moshiri Ala
Abstract excerpt
Purpose: The purpose of this study was to quantify the frequency and severity of ocular abnormalities affecting wild-type C57BL/6N mice, the most common strain used worldwide for the creation of single-gene knockouts. Methods: A total of 2773 animals (5546 eyes) were examined at one colony at UC Davis and in three more colonies at the Institut Clinique de la Souris in Strasbourg, France. Mice were examined at 15...
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