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Article

Review: the history and role of naturally occurring mouse models with Pde6b mutations.

Molecular vision - 20 Dec 2013

Han Juanjuan, Dinculescu Astra, Dai Xufeng, Du Wei, Smith W Clay, Pang Jijing

Abstract excerpt

Mouse models are useful tools for developing potential therapies for human inherited retinal diseases, such as retinitis pigmentosa (RP), since more strains are being identified with the same mutant genes and phenotypes as humans with corresponding retinal degenerative diseases. Mutations in the beta subunit of the human rod phosphodiesterase (PDE6B) gene are a common cause of autosomal recessive RP (arRP). This...

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Identifiers

PMID: 24367157
PMCID: PMC3869645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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