Article

Alternative splicing in 300 human cells and tissues is sparsely distributed and strongly associated with cell identity

2025-01-07

Abstract excerpt

<h4>ABSTRACT</h4> In eukaryotes, alternative splicing allows RNA sequences to be changed as required in their cellular context. While the use of gene expression without considering transcript isoforms is commonly used to classify cell types, the significance of alternative splicing to cell identity is not fully understood. Using data-driven classification and clustering methods, we analysed the RNA Atlas, an ultr...

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Literature Corpus work: 3e251fa6-3e12-50e7-bf80-ba5f0459769c
DOI: 10.1101/2025.01.06.631625

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