Article
Unannotated splicing regulatory elements in deep intron space.
Wiley interdisciplinary reviews. RNA - 1 Sept 2021
Conboy John G
Abstract excerpt
Deep intron space harbors a diverse array of splicing regulatory elements that cooperate with better-known exon-proximal elements to enforce proper tissue-specific and development-specific pre-mRNA processing. Many deep intron elements have been highly conserved through vertebrate evolution, yet remain poorly annotated in the human genome. Recursive splicing exons (RS-exons) and intraexons promote noncanonical,...
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